Publications


[ 1-99 ] [ 100-199 ] [ 200-299 ] [ 300-399 ] [ 400-499 ] [ 500- ] [ in press ]

596. Choi, S.H.; Mahankali, M.; Lee, S.J.; Hull, M.; Petrassi, M.H.; Chatterjee, A.K.; Schultz, P.G.; Jones, K.A.; Shen, W. "Targeted disruption of Myc-Max oncoprotein complex by a small molecule" ACS Chemical Biology, 12(11):2715-2719, 2017..
595. Bollong, M.J., Pietila, M.; Pearson, A.D.; Sarkar, T.R.; Ahmad, I.; Soundararajan, R.; Lyssiotis, C.A.; Mani, S.A.; Schultz, P.G.; Lairson, L.L. "A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers." P.N.A.S., 114(46):E9903-E9912, 2017..
594. Xuan, W.; Yao, A.; Schultz, P.G. "Genetically Encoded Fluorescent Probe for Detecting Sirtuins in Living Cells" J.A.C.S., 139(36):12350-12353, 2017..
593. Zambaldo, C.; Luo, X.; Mehta, A.P.; Schultz, P.G., "Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids" , J.A.C.S., 139(34):11646-11649, 2017..
592. Luo, X.;, Fu, G.; Wang, R.E.; Zhu, X.; Zambaldo, C.; Liu, R.; Liu, T.; Lyu, X.; Du, J.; Xuan, W.; Yao, A.; Reed. S.A.; Kang. M.; Zhang, Y.; Guo, H.; Huang, C.; Yang, P.; Wilsoh, I.A.; Schultz, P.G.; Wang, F., "Genetically Encoding Phosphotyrosine and its Nonhydrolyzable Analog in Bacteria" Nature Chemical Biology, 13(8):845-849, 2017..
591. Yu, S., Chen, E., Sherwood, L., Hull, M., Woods, A.K., Tremblay, M.S., "Ex Vivo Cell-Based Screening Platform for Modulators of Hepatosteatosis" ACS Chemical Biology, 12(7):1937-1946, 2017..
590. Lee, S.J., Bitar, A., Zou, H., Chao, E., Nguyen, H., Gonzalez, J., Caballero, D., Wang, D., Schultz, P.G., Shen, W., "A Novel Role for RARa Agonists as Apolipoprotein Clll Inhibitors." Scientific Reports, 7(1):5824, 2017..
589. Liu, T.; Jia, P.; Reed, S.A.; Luo, X.; Larman, B.H.; Schultz, P.G. "Construction and Screening of a Lentiviral Secretome Library" Cell Chemical Biology, 24(6):767-77, 2017..
588. Koh, M., Nasertorabi, F., Stevens, R.C., Schultz, P.G. "Generation of an orthogonal protein protein interface with a non-canonical amino acid" J.A.C.S., 139(16):5728-5731, 2017..
587. Xuan, W.; Shao, S.; Schultz, P.G. "Protein Crosslinking by Genetically Encoded Noncanonical Amino Acids with Reactive Aryl Carbamate Side Chains" Angewandte, 56(18):5096-5100, 2017..
586. Bollong, M.J., Yang, B., Vergani, N., Beyer, B.A., Chin, E.N., Zambaldo, C., Wang, D., Chatterjee, A.K., Lairson, L.L., Schultz, P.G. "Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis" Proc. Natl. Acam. Sci., 114(18):4679-4684, 2017..
585. Bouvard, C.; Lim, S.M.; Ludka, J.; Yazdani, N.; Woods, A.K.; Chatterjee, A.K.; Schultz, P.G.; Zhu, S. "Small molecule selectively suppresses MYC transcription in cancer cells" Proc. Natl. Acad. Sci., 114(13):3497-3502, 2017..
584. Liu, Y.; Wang, Y.; Zhang, Y.; Liu, T.; Jia, H.; Zou, H.; Fu, Q.; Zhang, Y.; Lu, L.; Chao, E.; Parker, H.; Nguyen-Tran, V.; Shen, W.; Wang, D.; Schultz, P.G.; Wang, F. "Rational Design of Dual Agonist-Antibody Fusions as Long-acting Therapeutic Hormones." ACS Chem. Biol., 11(11):2991-2995, 2016..
583. Mehta, A.P.; Li, H.; Reed, S.A.; Supekova, L.; Javahishvili, T.; Schultz, P.G. "Replacement of 2-deoxycytidine by 2-deoxycytidine Analogs in the E. coli Genome." J.A.C.S, 138(43):14230-14233, 2016..
582. Yu, S., Pearson, A.D., Lim, R.K., Rodgers, D.T., Li, S., Parker, H.B., Weglarz, M., Hampton, E.N., Bollong, M.J., Shen, J., Zambaldo, C., Wang, D., Woods, A.K., Wright, T.M., Schultz, P.G., Kazane, S.A., Young, T.S., Tremblay, M.S., "Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate." Mol. Ther., 10.1038/mt.2016.175, 2016..
581. Wang, R.E.; Wang, Y.; Zhang, Y.; Gabrelow, C.; Zhang, Y.; Chi, V.; Fu, Q.; Luo, X.; Wang, D.; Joseph, S.; Johnson, K.; Chatterjee, A.; Wright, T.M.; Nguyen-Tran, V.; Tejaro, J.; Theofilopoulos, A.N.; Schultz, P.G.; Wang, F. "Rational Design of a Kv1.3 Channel Blocking Antibody as a Selective Immunosuppressant" Proc. Natl. Acad. Sci., 113(41):11501-11506, 2016..
580. Wang, Y.; Du, J.; Zou, H.; Liu, Y.; Zhang, Y.; Gonzalez, J.; Chao, E.; Lu, L.; Parker, H.; Nguyen-Tran, V.; Shen, W.; Wang, D.; Schultz, P.G., Wang, F. "Multi-functional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-dependent Insulinotropic Polypeptide Receptors." Angew. Chem. Int. Ed. Engl, 55(40):12475-8, 2016..
579. Abdeen, S.; Salim, N.; Mammadova, N.; Summers, C.M.; Goldsmith-Pestana, K.; McMahon-Pratt, D.; Schultz, P.G.; Horwich, A.L.; Chapman, E.; Johnson, S.M "Targeting the HSP60/10 Chaperonin Systems of Trypanosoma Brucei as a Strategy for Treating African Sleeping Sickness." Bioorganic & Medicinal Chemistry Letters, pii: S0960-894X(16)30992-1, 2016..
578. Luo, X.; Wang, T.A.; Zhang, Y.; Wang, F.; Schultz, P.G. "Stabilizing Protein Motifs with a Genetically Encoded Metal-Ion Chelator" Cell Chemical Biology, 23(9):1098-102, 2016..
577. Zhang, Z.; English, B.; Grimm, J.B.; Kazane, S.; Hu, W.; Tsai, A.; Inouye, C.; Schultz, P.G.; Lavis, L.D.; Revyakin, A.; Tjian, R., "Rapid Dynamics of General Transcription Factor TFIIB Binding During Preinitiation Complex Assembly Revealed by Single-Molecule Analysis." Genes and Development, 30(18):2106-2118, 2016..
576. Xuan, W.; Li, J.; Luo, X.; Schultz, P.G. "Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins." Angew. Chem. Int. Ed. Engl., 55(34):10065-8, 2016..
575. Abdeen, S.; Salim, N.; Mammadova, N.; Summers, C.M.; Frankson, R.; Ambrose, A.J.; Anderson, G.G.; Schultz, P.G.; Horwich, A.L.; Chapman, E.; Johnson, S.M., "GroEL/ES Inhibitors as Potential Antibiotics." Bioorg. Med. Chem. Lett., 26(13):3127-3, 2016..
574. Cao,Y.; Rodgers, D.T.; Du, J.; Ahmad, I.; Hampton, E.N.; Ma, J.S.; Mazagova, M.; Choi, S.; Yun, H.Y.; Xiao, H.; Yang, P.; Luo, X.; Lim, R.K.V.; Pugh, H.M.; Wang, F.; Kazane, S.A.; Wright, T.M.; Kim, C.H.; Schultz, P.G.; Young, T.S., "Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer." Angew. Chem. Int. Ed. Engl., 55(26):7520-4, 2016..
573. Xiao, H., Schultz, P.G., "At the Interface of Chemical and Biological Synthesis: An Expanded Genetic Code" Cold Spring Harb. Perspect. Biol., pii: a023945, 2016..
572. Mehta, A.P.; Li, H.; Reed, S.A.; Supekova, L.; Javahishvili, T.; Schultz, P.G. "Replacement of Thymidine by a Modified Base in the Escherichia coli Genome" J.A.C.S., 138(23):7272-5, 2016..
571. Lee, T., Kang, M., Kim, C.H., Schultz, P.G, Chapman, E., Deniz, A. "Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to Enable Single-Molecule FRET Studies of p97 Folding" ChemBioChem, 17(11):981-4, 2016..
570. Liu, T.; Wang, Y.; Luo, X.; Li, J.; Reed, S.A.; Xiao, H.; Young, T.S.; Schultz, P.G. "Enhancing Protein Stability with Extended Disulfide Bonds." Proc. Natl. Acad. Sci., 113(21):5910-5, 2016..
569. Yang. P.; Zou, H.; Chao. E.; Sherwood, L.; Nunez, V.; Keeney, M.; Ghartey-Tagoe, E.; Ding, Z.; Quirino, H.; Luo, X.; Welzel, G.; Chen, G.; Singh. P.; Woods. A.K.; Schultz, P.G.; Shen, W., "Engineering a Long-Acting, Potent GLP-1 Analogue for Microstructure-Based Transdermal Delivery." Proc. Natl. Acad. Sci., 113(15):4140-5., 2016..
568. Luo, X.; Zambaldo, C.; Liu, T.; Zhang, Y.; Xuan, W.; Wang, C.; Reed, S.A.; Yang, P.; Wang, R.E.; Javahishvilli, T.; Schultz, P.G.; Young, T.S. "Recombinant Thiopeptides with Noncanonical Amino Acids" , Proc. Natl. Acad. Sci., 113(13):3615-20, 2016..
567. Ma. J., Young, K.J.; Kazane, S.; Choi, S.H.; Yoon, H.Y., Kim, M., Rodger, D.; Pugh, H.; Singer, O.; Sun, Sophie, S.; Fonslow, B.; Kochenderfer, J.; Wright, T.; Schultz, P.G.; Young, T.; Kim, C.H.; Cao, Y. "A Versatile Strategy for Controlling the Specificity and Activity of Engineered T Cells." Proc. Natl. Acad. Sci., E450-8, 2016..
566. Rodgers, D.; Mazagova, M.; Hampton, E.; Cao, Y.; Ramadoss, N.; Hardy, I.; Schulman, A.; Du, J.; Wang, F.; Singer, O.; Ma, J.; Nunez, V.; Shen, J.; Woods, A.; Wright, T.; Schultz, P.G.; Kim, C. H.; Young, T., "Switch-Mediated Activation and Retargeting of CAR T cells for B cell Malignancies." Proc. Natl. Acad. Sci., E459-68, 2016..
565. Muppid, A., Zou, H., Chao, E., Yang P., Sherwood, L., Nunez, V., Woods, A., Schultz, P.G., Lin, Q., Shen, W., "Design of Potent, Proteolytically Stable Oxyntomodulin Analogs." Angewandte, 11(2):324-8, 2016..
564. Lim, R.K.V, Yu, S., Chen, B., Li, S., Nam-Jung, K., Cao, Y., Chi, V., Kim, J.Y., Chattergee, A.K., Tremblay, M.S., Schultz, P.G., Kazane, S.A., "Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate." ACS Paragon Plus, 26(11):2216-22, 2015..
563. Luo, X. Liu, T. Wang, Y.Jia, H, Zhang, Y, Caballero, D. Du, J. Wang, R, Wang, D. Schultz, P.G., Wang, F., "An Epitope-Specific Respiratory Syncytial Virus Vaccine Based on an Antibody Scaffold." Angew Chem. Int. Ed. Engl., 10.1002/anie.201507928, 2015.
562. Bollong, M., Hwayoung, Y., Sherwood, L., Woods, A., Lairson, L., Schultz, P.G., "A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer." ACS Chem. Biol. 10(10), 2193-8, 2015..
561. Xiao, H., Xuan, W., Shao, S., Liu, T., Schultz, P.G., "Genetic Incorporation of e-N-2-Hydroxyisobutyryl-lysine into Re-combinant Histones." ACS Chem. Bio., 1599-603, 2015..
560. Xiao, H., Nasertorabi, F., Seihyun, C., Won Han, G., Reed, S.A., Stevens, R.C., Schultz, P.G., "Exploring the Potential Impact of an Expanded Genetic Code on Protein Function" Proc. Natl. Acad. Sci., 112(22):6961-6, 2015..
559. Cao, Y., Axup, J.Y., Ma, J.S.Y., Wang, R.E., Choi, S., Tardif, V., Lim, R., Pugh, H., Lawson, B.R., Welzel, G., Kazane, S.A., Sun, Y., Tian, F., Srinagesh, S., Javahishvili, T., Schultz, P.S., Kim, C.H., "Multi-format T-cell Engaging Bispecific Antibodies Targeting Human Breast Cancers." Angew. Chem. Int. Ed. Engl., 54(24):7022-7, 2015..
558. Harbut, M., Vilcheze, C., Luo, X., Hensler, M.E., Guo, H., Yang, B., Chatterjee, A.K., Nizet, V., Jacobs, W.R., Schultz, P.G., Wang, F., "Auranofin Exerts Broad-Spectrum Bactericidal Activities by Targeting Thiol-Redox Homeostasis." Proc. Natl. Acad. Sci., 112(14):4453-4458, 2015..
557. Zhang, Y., Liu, Y., Wang, Y., Schultz, P.G., Wang, F., "Rational Design of Humanized Dual-Agonist Antibodies." J. Am. Chem. Soc., 137(1):38-41, 2015..
556. Wang, R., Liu, T., Wang, Y., Cao, Y., Du, J., Luo, X., Deshmukh, V., Kim, C.H., Lawson, B.R., Tremblay, M.S., Young, T.S., Kazane, S.A., Wang, F., Schultz, P.G., "An Immunosuppressive Antibody-Drug Conjugate" J. Am. Chem. Soc., 137(9):3229-32, 2015..
555. Liu, T., Fu, G., Luo, X., Liu, Y., Wang, Y., Wang, R., Schultz, P.G., Wang, F., "Rational Design of Antibody Protease Inhibitors." J. Am. Chem. Soc., 137(12):4042-5, 2015..
554. Zhang, Y., Liu, Y., Zou, H., Wang, Y., Caballero, D., Gonzalez, J., Chao, E., Welzel, G., Shen, W., Wang, D., Schultz, P.G., Wang, F. "A Versatile Approach to the Generation of Human Antibody-CDR Fusion Proteins with Agonist Activities." J. Am. Chem. Soc., 137(1):38-41, 2015..
553. Kim, M.S., Ma, J.S.Y., Yun, H., Cao, Y., Kim, J.Y., Chi, V., Wang, D., Woods, A., Sherwood, L., Caballero, C., Gonzalez, J., Schultz, P.G., Young, T.S., Kim, C.H., "Redirection of Genetically Engineered CAR-T cells using Bifunctional Small Molecules." J. Am. Chem. Soc., 137(8):2832-5, 2015..
552. Zhang, Y., Zou, H., Wang, Y., Caballero, D., Gonzalez, J., Chao, E., Welzel, G., Shen, W., Wang, D., Schultz, P.G., Wang, F., " Rational Design of a Humanized Glucagon-Like Peptide-1 Receptor Agonist Antibody." Angew Chem. Int. Ed. Engl., 54(7):2126-30, 2015..
551. Liu, T., Zhang, Y., Liu, Y., Wang, Y., Jia, H., Kang, M., Luo, X., Caballero, D., Gonzalez, J., Wang, D., Woods, A., Schultz, P.G., Wang, F., " Functional Human Antibody CDR Fusions as Long-Acting Therapeutic Endocrine Agonists." Proc. Nat. Acad. Sci., 3; 112(5):1356-61, 2015..
550. Pearson, A.D., Mills, J.H., Song, Y., Nasertorabi, F., Han, G.W., Baker, D., Stevens, R.C., Schultz, P.G., " Trapping a Transition State in a Computationally Designed Protein Bottle." Science, 347(6224):863-7, 2015..
549. Decker, R.S., Koyama, E., Enomoto-Iwamoto, M., Maye, P., Rowe, D., Zhu, S., Schultz, P.G., Pacifici, M., " Mouse Limb Skeletal Growth and Synovial Joint Development are Greatly Enhanced by Kartogenin." Dev. Biol., 15; 395 (2):255-67, 2014..
548. Kularatne, S., Deshmukh, V., Ma, J., Tardif, V., Lim, R., Pugh, H., Sun, Y., Manibusan, A., Sellers, A., Barnett, R., Srinagesh, S., Forsyth, J.S., Hassenpflug, W., Tian, F., Javashishvili, T., Felding-Habermann, B., Lawson, B.R., Kazane, S., Schultz, P.G., " A CXCR4-Targeted Site-Specific Antibody-Drug Conjugate." Angew. Chem., 53(44):11863-7, 2014..
547. Lu, H., Zhou, Q., Deshmukh, V., Phull, H., Ma, J., Tardif, V., Bouvard, C., Lawson, B.R., Zhu, S., Zhang, Y., Choi, S., Kim, C.H., Schultz, P.G., "Targeting Human C-Type Lectin-Like Molecule-1 (CLL1) by a Bispecific Antibody for Acute Myeloid Leukemia Immunotherapy." Angew Chem Int Ed Engl., 53(37):9841-5, 2014..
546. Liu, T, Liu Y, Wang Y, Hull M, Schultz P, Wang F., "Rational Design of CXCR4 Specific Antibodies with Elongated CDRs." J Am Chem Soc, 136(30):10557-60, 2014..
545. Sun, S.B., Schultz, P.G., Kim, C.H, "Therapeutic Applications of an Expanded Genetic Code." ChemBioChem, 15(12);1721-9, 2014..
544. Larman H.B, Scott E.R., Wogan M, Torkamani A., Schultz P.G., "Sensitive, multiplex and direct quantification of RNA sequences using a modified RASL assay." Nucleic Acids Res, 42(14):9146-57, 2014..
543. Furman, J.L., Kang, M., Choi, S., Cao, Y., Wold, E.D., Sun, S.B., Smider, V.V., Kim, C., Schultz, P.G., "A genetically encoded aza-Michael acceptor for covalent crosslinking of protein-receptor complexes." J Am Chem Soc, 136(23):8411-8417, 2014..
542. Chatterjee, A., Lajoie, M.J., Xiao, H., Church, G.M., Schultz, P.G., "A Bacterial Strain with a Unique Quadruplet Codon Specifying Nonnative Amino Acids." ChemBioChem, ASAP, 2014..
541. Xiao, H., Peters, F.B., Yang, P.Y., Reed, S., Chittuluru, J.R., Schultz, P.G., "Genetic Incorporation of Histidine Derivatives Using an Engineered Pyrrolysyl-tRNA Synthetase." ACS Chem Biol, 9(5);1092-1096, 2014..
540. Kang, M., Light, K., Ai, H., Shen, W., Kim, C., Chen, P.R., Lee, H., Solomon, E.I., Schultz, P.G., "Evolution of Iron (II)-Finger Peptides Using a Biphridyl Amino Acid." ChemBioChem, 15(6);822-825, 2014..
539. Javahishvili, T., Manibusan, A., Srinagesh, S., Lee, D., Ensari, S., Shimazu, M., Schultz, P.G., "The Role of tRNA Orthogonality in an Expanded Genetic Code." ACS Chem Biol, 9(4);874-879, 2014..
538. Tian, Feng, Lu, Y., Manibusan, A., Sellers, A., Tran, H., Sun, Y., Phuong, T., Barnett, R., Hehli, B., Song, F., DeGuzman, M., Ensar, S., Pinkstaff, J., Sullivan, L., Biroc, S., Cho, P., Schultz, P.G., DiJoseoph, J., Dougher, M., Ma, D., Dushin, R.G., Leal, M., Tchistiakova, L., Feyfant, E., Gerber, H.P., Sapra, P., "A general approach to site-specific antibody drug conjugates." Proc Natl Acad Sci, 111(5):1766-71, 2014..
537. Rust, Heather, Subramanian, V., West, G. M., Young D.D., Schultz, P.G., Thompson, P.R., "Using unnatural amino acid mutagensis to probe the regulation of PRMT1." 9(3);649-655, 2014., .
536. Zhang, Y., Goswami, D., Wang, D., Wang, T., Sen, S., Magliery, T.J., Griffin, P.R., Wang, F, Schultz, P.G., "An antibody with a variable region coiled-coil knob domain." Angew Chem Int Ed Engl., 53(1):132-5, 2014..
535. Xiao, H., Chatterjee, A., Choi, S., Bajjuri, K.M., Sinha, S.C., Schultz, P.G., "Genetic incorporation of multiple unnatural amino acids into proteins into mammalian cells." Angew Chem Int Ed Engl., 52(52):14080-3, 2013..
534. Liu, J., Pan, S., Hsieh, M., Ng, N., Sun, F., Kasibhatla, S., Schuller, A.G., Li, A., Cheng, D., Li, J., Tompkins, C., Pferdekamper, A., Steffy, A., Chen, J., Kowal, C., Phung, V., Guo, G., Wang, Y., Graham, M., Brenner, J.D., Li, C., Wang, T., Villarroel, M.C., Schultz, P.G., Wu, X., McNamara, P., Sellers, W.R., Petruzzelli, L., Boral, A., Seidal, H.M., Mclaughlin, M.E., Che, J., Carey, T.E., Vanasse, G., Harris, J.L., "Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974." Proc Natl Acad Sci, 110(50):20224-9, 2013..
533. Kularatne, S.A., Deshmukh, V., Gymnopoulous, M., Biroc, S., Srinagesh, S., Sun, Y., Zou, N., Sumatz, M., Pintoki, J., Ensari, S., Malibusan, A., Axup, J., Kim, C., Smider, V.V., Javahishvili, T., Schultz, P.G., "Recruiting Cytotoxic T Cells to Folate-Receptor-Positive Cancer Cells." Angew Chem Int Ed Engl., 152(46):12101-4, 2013..
532. Kessel, C., Nandakumar, K.S., Peters, F.B., Schultz, P.G., Holmdahl, R., "A single functional group substitution in C5a breaks B and T cell tolerance and protects from experimental arthritis" Arthritis Rheum, 66(3):610-621, 2013..
531. Niu, W., Schultz, P.G., Guo, J., "An expanded genetic code in mammalian cells with a functional quadruplet codon." ACS Chem Biol, 8(7):1407-1411, 2013..
530. Swoboda, J.G., Elliott, J., Deshmukh, V., de Lichtervelde, L., Shen, W., Tremblay, M.S., Cho, C.Y., Lu, B., Girman, S., Wang, S., Schultz, P.G., "Small molecule mediated proliferation of primary retinal pigmented epithelial cells." ACS Chem Biol., 8(7):1407-1411, 2013..
529. Kim, C., Axup, J.Y., Lawson, B., Yun, H., Tardif, V., Choi, S., Zhou, Q., Dubrovska, A., Biroc, S.L., Marsden, R., Pinkstaff, J., Smider, V.V., Schultz, P.G., "A bispecific small molecule antibody conjugate targeting prostate cancer." Proc Natl Acad Sci USA, 110(44):17796-801, 2013..
528. Lajoie, M.J., Rovner. A.J., Goodman, D.B., Aerni, H., Mercer, J.A., Wang, H.H., Carr, P.A., Schultz, P.G., Jacobson, J.M., Rinehart, J., Church, G.M., Isaacs, F.J., "Genomically recoded organisms expand biological functions," Science, 342(6156):357-60, 2013..
527. Zhang, Y., Wang, D., Welzel, G., Wang, Y., Schultz, P.G., Wang, F., "An antibody CDR3-erythropoietin fusion protein." ACS Chem Bio, 8(10):2117-21, 2013.
526. Deshmukh, V.A., Tardif, V., Lyssiotis, C.A., Green, C.C., Kerman, B., Kim., H.J., Padmanabhan, K., Swoboda, J., Ahmad, I., Kondo, T., Gage, F.H., Theofilopoulos, A.N., Lawson, B.R., Schultz, P.G., Lairson, L.L. "A regenerative approach to the treatment of multiple sclerosis." Nature, 502(7471):327-32, 2013..
525. Lu, H., Wang. D., Kazane, S.A., Javahishvili, T., Tian, F., Song, F., Sellers, A., Barnett, B., Schultz, P.G., "Site-specific antibody-polymer conjugates for siRNA delivery." J Am Chem Soc, 135(37):13885-91, 2013..
524. Chatterjee, A., Guo., J., Lee, H., Schultz, P., "A genetically encoded fluorescent probe in mammallian cells." J Am Chem Soc, 135(34):12540-3, 2013..
523. Zhang, Y., Wang, D., Lichtervelde, L., Sun, S.B., Smider, V.V., Schultz, P.G., Wang, F., "Functional antibody CDR3 fusion proteins with enhanced pharmacological properties." Angew Chem Int Ed Engl, 5;52(32):8295-8, 2013..
522. Chatterjee, A., Xiao, H., Bollong, M., Ai, H., Schultz, P.G., "An efficient viral delivery system for unnatural amino acid mutagensis in mammalian cells." Proc Natl Acad Sci USA, 110(29):11803-8, 2013..
521. Sun, S., Sen, S., Kim, N., Magliery, T., Schultz, P.G., Wang, F., "A mutational analysis of 48G7 reveals that somatic hypermutation affects both antibody stability and binding affinity." J Am Chem Soc, 135(27):9980-9983, 2013..
520. Wang, F., Sambandan, D., Halder, R., Wang, J., Batt, S., Weinrick, B.C., Ahmad, I., Yang, P., Zhang, Y., Kim, J., Hassani, M., Huszar, S., Trefzer, C., Chatterjee, A., Johnsson, K., Mikusove, K., Besra, G., Futterer, K., Jacobs, W.R., Schultz, P.G., "Identification of a small molecule with activity against drug-resistent and persistant tuberculosis." Proc Natl Acad Sci, 110(27):E2510-7, 2013..
519. Wang, F., Ekiert, D.C., Ahmad, I., Li, W., Zhang, Y., Torkamani, A., Raudsepp, T., Criscitiello, M.F., Wilson, I.A., Schultz, P.G., Smider, V.V., "Reshaping antibody diversity." Cell, 153(6):1379-9, 2013..
518. Kim, C., Axup, J., Schultz, P.G., "Protein conjugation with genetically encoded unnatural amino acids," Curr Opin Chem Biol, 17(3):412-9, 2013..
517. de Lichtervelde, L., Boitano, A.E., Wang, Y., Krastel, P., Petersen, F., Cooke, M.P., Schultz, P.G., "Eupalinilide E inhibits erythropoiesis and promotes the expansion of hematopoietic progenitor cells," ACS Chem. Bio., 8(5);866-870, 2013..
516. Chatterjee, A., Xiao, H., Yang, P., Soundararajan, G., Schultz, P.G., "A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli," Angew Chem Int Ed Engl, 52(19):5106-9, 2013..
515. Day, J.W., Kim, C., Smider, V.V., Schultz, P.G. "Identification of metal ion binding peptides containing unnatural amino acids by phage display." Bioorg. Med. Chem. Lett, 23(9):2598-600, 2013.
514. Wang, F., Sen, S., Zhang, Y., Ahmad, I., Zhu, X., Wilson, I.A., Smider, V.V., Magliery, T.J., Schultz, P.G. "Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation." Proc. Nat. Acad. Sci., 110(11):4261-6, 2013..
513. Chatterjee, A., Sun, S.B., Furman, J.L., Xiao, H., Schultz, P.G., "A versatile platform for single and multiple unnatural amino acid mutagenesis in Escherichia coli," Biochemistry, 52(10):1828-1837, 2013., .
512. Shen, W., Tremblay, M.S., Deshmukh, V.A., Wawng, W., Filipi, C.M., Harb, G., Zhang, Y., Kamireddy, A., Baaten, J.E., Jin, Q., Wu, T., Swoboda, J.G., Cho, C.Y., Laffitte, B.A., McNamara, P., Glynne, R., Wu, X., Herman, A.E., Schultz, P.G., "A small molecule inducer of β cell proilferation indentified by high-throughput screening." J. Am. Chem. Soc., 135(5):1669-72, 2013..
511. Lairson, L. L., Lyssiotis, C.A., Zhu, S., Schultz, P.G., "Small molecule-based approaches to adult stem cell therapies." Ann. Rev. Pharmacol. Toxicol, 53:107-25, 2013.
510. Kazane, S.A., Axup, A.Y., Kim, C., Ciobanu, M., Wold, E.D., Barluenga, S., Hutchins, B.A., Schultz, P.G., Winssinger, N., Smider, V.V. "Self-assembled antibody multimers through peptide nucleic acid conjugation." J. Am. Chem. Soc., 135(1):340-6, 2013.
509. Axup, J.A., Bajjuri, K.M., Ritland, M., Hutchins, B.M., Kim, C., Kazane, S.A., Halder, R., Forsyth, J.S., Santidrian, A.F., Stafin, K., Liu, Y., Tran, H., Seller, A.J., Biroc, S.L., Szydlik, A., Pinkstaff, J.K., Tian, F., Sinha, S.C., Felding-Habermann, B., Smider, V.V., Schultz, P.G. "Synthesis of site-specific antibody-drug conjugates using unnatural amino acids." Proc. Nat. Acad. Sci., 109(40):16101-16106, 2012.
508. Guo, J., Wang, F., Schultz, P.G. "Unnatural amino acid mutagensis of fluorescent proteins." Angewante Chemie, 51(40):10132-10135, 2012.
507. Wang, D., Wang, J., Meeusen, S., Bonamy, G., Brusch, R.G., Turk, C., Yang, P., Schultz, P.G. "A small molecule promotes mitochondrial fusion in mammalian cells." Angewante Chemie Int. Ed. Engl, 51(40):10132-10135, 2012.
506. Hirota, T., Lee, J.W., St. John., P.C., Sawa, M., Iwaisako, K., Noguchi, T., Pongsawakul, P.Y., Sonntag, T., Welsh, D.K., Brenner, D.A., Doyle, J., Schultz, P.G., Kay, S.A. "Identification of small molecule activators of cryptochrome." Science, 337(6098):1094-1097, 2012.
505. Boitano, A.E., de Lichtervelde, L., Snead, J.L., Cooke, M.P., Schultz, P.G. "A platelet derived growth factor receptor antagonist." Proc. Nat. Acad. Sci, 109(35):14019-14022, 2012.
504. Chatterjee, A., Xiao, H., Schultz, P.G. "Evolution of multiple, mutally orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli." Proc. Nat. Acad. Sci., 109(37):14841-14846, 2012.
503. de Lichtervelde, L., Antal, C.E., Boitano, A.E., Wang, Y., Krastel, P., Petersen, F., Newton, A.C., Cooke, M.P., Schultz, P.G. "Euphohelisocopin A is a PKC activator capable of inducing macrophage differentiation." Chemistry and Biology, 19(8):944-1000, 2012.
502. Kim, C., Kang, M., Kim, H., Chatterjee, A., Schultz, P.G. "Site-specific incorporation of ε-N-crotonyllysine into histones." Angew. Chem., 51(29):7246-9, 2012.
501. Dubrovska, A., Hartung, A., Bouchez, L.C., Walker, J.R., Cho, C.Y., Schultz, P.G. "CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signaling." Br. J. Cancer, 107(1):43-52, 2012.
500. Kim, C., Axup, J.Y., Dubrovska, A., Kazane, S.A., Hutchins, B.A., Wold, E., Smider, V.V., Schultz, P.G. "Synthesis of bispecific antibodies with genetically encoded unnatural amino acids." J. Am. Chem. Soc., 134(24):9918-21, 2012.