Publications


[ 1-99 ] [ 100-199 ] [ 200-299 ] [ 300-399 ] [ 400-499 ] [ 500- ] [ in press ]

547. Lu, H., Zhou, Q., Deshmukh, V., Phull, H., Ma, J., Tardif, V., Bouvard, C., Lawson, B.R., Zhu, S., Zhang, Y., Choi, S., Kim, C.H., Schultz, P.G., "Targeting Human C-Type Lectin-Like Molecule-1 (CLL1) by a Bispecific Antibody for Acute Myeloid Leukemia Immunotherapy." Angew Chem Int Ed Engl., 53(37):9841-5, 2014..
546. Liu, T, Liu Y, Wang Y, Hull M, Schultz P, Wang F., "Rational Design of CXCR4 Specific Antibodies with Elongated CDRs." J Am Chem Soc, 136(30):10557-60, 2014..
545. Sun, S.B., Schultz, P.G., Kim, C.H, "Therapeutic Applications of an Expanded Genetic Code." ChemBioChem, 15(12);1721-9, 2014..
544. Larman H.B, Scott E.R., Wogan M, Torkamani A., Schultz P.G., "Sensitive, multiplex and direct quantification of RNA sequences using a modified RASL assay." Nucleic Acids Res, 42(14):9146-57, 2014..
543. Furman, J.L., Kang, M., Choi, S., Cao, Y., Wold, E.D., Sun, S.B., Smider, V.V., Kim, C., Schultz, P.G., "A genetically encoded aza-Michael acceptor for covalent crosslinking of protein-receptor complexes." J Am Chem Soc, 136(23):8411-8417, 2014..
542. Chatterjee, A., Lajoie, M.J., Xiao, H., Church, G.M., Schultz, P.G., "A Bacterial Strain with a Unique Quadruplet Codon Specifying Nonnative Amino Acids." ChemBioChem, ASAP, 2014..
541. Xiao, H., Peters, F.B., Yang, P.Y., Reed, S., Chittuluru, J.R., Schultz, P.G., "Genetic Incorporation of Histidine Derivatives Using an Engineered Pyrrolysyl-tRNA Synthetase." ACS Chem Biol, 9(5);1092-1096, 2014..
540. Kang, M., Light, K., Ai, H., Shen, W., Kim, C., Chen, P.R., Lee, H., Solomon, E.I., Schultz, P.G., "Evolution of Iron (II)-Finger Peptides Using a Biphridyl Amino Acid." ChemBioChem, 15(6);822-825, 2014..
539. Javahishvili, T., Manibusan, A., Srinagesh, S., Lee, D., Ensari, S., Shimazu, M., Schultz, P.G., "The Role of tRNA Orthogonality in an Expanded Genetic Code." ACS Chem Biol, 9(4);874-879, 2014..
538. Tian, Feng, Lu, Y., Manibusan, A., Sellers, A., Tran, H., Sun, Y., Phuong, T., Barnett, R., Hehli, B., Song, F., DeGuzman, M., Ensar, S., Pinkstaff, J., Sullivan, L., Biroc, S., Cho, P., Schultz, P.G., DiJoseoph, J., Dougher, M., Ma, D., Dushin, R.G., Leal, M., Tchistiakova, L., Feyfant, E., Gerber, H.P., Sapra, P., "A general approach to site-specific antibody drug conjugates." Proc Natl Acad Sci, 111(5):1766-71, 2014..
537. Rust, Heather, Subramanian, V., West, G. M., Young D.D., Schultz, P.G., Thompson, P.R., "Using unnatural amino acid mutagensis to probe the regulation of PRMT1." 9(3);649-655, 2014., .
536. Zhang, Y., Goswami, D., Wang, D., Wang, T., Sen, S., Magliery, T.J., Griffin, P.R., Wang, F, Schultz, P.G., "An antibody with a variable region coiled-coil knob domain." Angew Chem Int Ed Engl., 53(1):132-5, 2014..
535. Xiao, H., Chatterjee, A., Choi, S., Bajjuri, K.M., Sinha, S.C., Schultz, P.G., "Genetic incorporation of multiple unnatural amino acids into proteins into mammalian cells." Angew Chem Int Ed Engl., 52(52):14080-3, 2013..
534. Liu, J., Pan, S., Hsieh, M., Ng, N., Sun, F., Kasibhatla, S., Schuller, A.G., Li, A., Cheng, D., Li, J., Tompkins, C., Pferdekamper, A., Steffy, A., Chen, J., Kowal, C., Phung, V., Guo, G., Wang, Y., Graham, M., Brenner, J.D., Li, C., Wang, T., Villarroel, M.C., Schultz, P.G., Wu, X., McNamara, P., Sellers, W.R., Petruzzelli, L., Boral, A., Seidal, H.M., Mclaughlin, M.E., Che, J., Carey, T.E., Vanasse, G., Harris, J.L., "Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974." Proc Natl Acad Sci, 110(50):20224-9, 2013..
533. Kularatne, S.A., Deshmukh, V., Gymnopoulous, M., Biroc, S., Srinagesh, S., Sun, Y., Zou, N., Sumatz, M., Pintoki, J., Ensari, S., Malibusan, A., Axup, J., Kim, C., Smider, V.V., Javahishvili, T., Schultz, P.G., "Recruiting Cytotoxic T Cells to Folate-Receptor-Positive Cancer Cells." Angew Chem Int Ed Engl., 152(46):12101-4, 2013..
532. Kessel, C., Nandakumar, K.S., Peters, F.B., Schultz, P.G., Holmdahl, R., "A single functional group substitution in C5a breaks B and T cell tolerance and protects from experimental arthritis" Arthritis Rheum, 66(3):610-621, 2013..
531. Niu, W., Schultz, P.G., Guo, J., "An expanded genetic code in mammalian cells with a functional quadruplet codon." ACS Chem Biol, 8(7):1407-1411, 2013..
530. Swoboda, J.G., Elliott, J., Deshmukh, V., de Lichtervelde, L., Shen, W., Tremblay, M.S., Cho, C.Y., Lu, B., Girman, S., Wang, S., Schultz, P.G., "Small molecule mediated proliferation of primary retinal pigmented epithelial cells." ACS Chem Biol., 8(7):1407-1411, 2013..
529. Kim, C., Axup, J.Y., Lawson, B., Yun, H., Tardif, V., Choi, S., Zhou, Q., Dubrovska, A., Biroc, S.L., Marsden, R., Pinkstaff, J., Smider, V.V., Schultz, P.G., "A bispecific small molecule antibody conjugate targeting prostate cancer." Proc Natl Acad Sci USA, 110(44):17796-801, 2013..
528. Lajoie, M.J., Rovner. A.J., Goodman, D.B., Aerni, H., Mercer, J.A., Wang, H.H., Carr, P.A., Schultz, P.G., Jacobson, J.M., Rinehart, J., Church, G.M., Isaacs, F.J., "Genomically recoded organisms expand biological functions," Science, 342(6156):357-60, 2013..
527. Zhang, Y., Wang, D., Welzel, G., Wang, Y., Schultz, P.G., Wang, F., "An antibody CDR3-erythropoietin fusion protein." ACS Chem Bio, 8(10):2117-21, 2013.
526. Deshmukh, V.A., Tardif, V., Lyssiotis, C.A., Green, C.C., Kerman, B., Kim., H.J., Padmanabhan, K., Swoboda, J., Ahmad, I., Kondo, T., Gage, F.H., Theofilopoulos, A.N., Lawson, B.R., Schultz, P.G., Lairson, L.L. "A regenerative approach to the treatment of multiple sclerosis." Nature, 502(7471):327-32, 2013..
525. Lu, H., Wang. D., Kazane, S.A., Javahishvili, T., Tian, F., Song, F., Sellers, A., Barnett, B., Schultz, P.G., "Site-specific antibody-polymer conjugates for siRNA delivery." J Am Chem Soc, 135(37):13885-91, 2013..
524. Chatterjee, A., Guo., J., Lee, H., Schultz, P., "A genetically encoded fluorescent probe in mammallian cells." J Am Chem Soc, 135(34):12540-3, 2013..
523. Zhang, Y., Wang, D., Lichtervelde, L., Sun, S.B., Smider, V.V., Schultz, P.G., Wang, F., "Functional antibody CDR3 fusion proteins with enhanced pharmacological properties." Angew Chem Int Ed Engl, 5;52(32):8295-8, 2013..
522. Chatterjee, A., Xiao, H., Bollong, M., Ai, H., Schultz, P.G., "An efficient viral delivery system for unnatural amino acid mutagensis in mammalian cells." Proc Natl Acad Sci USA, 110(29):11803-8, 2013..
521. Sun, S., Sen, S., Kim, N., Magliery, T., Schultz, P.G., Wang, F., "A mutational analysis of 48G7 reveals that somatic hypermutation affects both antibody stability and binding affinity." J Am Chem Soc, 135(27):9980-9983, 2013..
520. Wang, F., Sambandan, D., Halder, R., Wang, J., Batt, S., Weinrick, B.C., Ahmad, I., Yang, P., Zhang, Y., Kim, J., Hassani, M., Huszar, S., Trefzer, C., Chatterjee, A., Johnsson, K., Mikusove, K., Besra, G., Futterer, K., Jacobs, W.R., Schultz, P.G., "Identification of a small molecule with activity against drug-resistent and persistant tuberculosis." Proc Natl Acad Sci, 110(27):E2510-7, 2013..
519. Wang, F., Ekiert, D.C., Ahmad, I., Li, W., Zhang, Y., Torkamani, A., Raudsepp, T., Criscitiello, M.F., Wilson, I.A., Schultz, P.G., Smider, V.V., "Reshaping antibody diversity." Cell, 153(6):1379-9, 2013..
518. Kim, C., Axup, J., Schultz, P.G., "Protein conjugation with genetically encoded unnatural amino acids," Curr Opin Chem Biol, 17(3):412-9, 2013..
517. de Lichtervelde, L., Boitano, A.E., Wang, Y., Krastel, P., Petersen, F., Cooke, M.P., Schultz, P.G., "Eupalinilide E inhibits erythropoiesis and promotes the expansion of hematopoietic progenitor cells," ACS Chem. Bio., 8(5);866-870, 2013..
516. Chatterjee, A., Xiao, H., Yang, P., Soundararajan, G., Schultz, P.G., "A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli," Angew Chem Int Ed Engl, 52(19):5106-9, 2013..
515. Day, J.W., Kim, C., Smider, V.V., Schultz, P.G. "Identification of metal ion binding peptides containing unnatural amino acids by phage display." Bioorg. Med. Chem. Lett, 23(9):2598-600, 2013.
514. Wang, F., Sen, S., Zhang, Y., Ahmad, I., Zhu, X., Wilson, I.A., Smider, V.V., Magliery, T.J., Schultz, P.G. "Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation." Proc. Nat. Acad. Sci., 110(11):4261-6, 2013..
513. Chatterjee, A., Sun, S.B., Furman, J.L., Xiao, H., Schultz, P.G., "A versatile platform for single and multiple unnatural amino acid mutagenesis in Escherichia coli," Biochemistry, 52(10):1828-1837, 2013., .
512. Shen, W., Tremblay, M.S., Deshmukh, V.A., Wawng, W., Filipi, C.M., Harb, G., Zhang, Y., Kamireddy, A., Baaten, J.E., Jin, Q., Wu, T., Swoboda, J.G., Cho, C.Y., Laffitte, B.A., McNamara, P., Glynne, R., Wu, X., Herman, A.E., Schultz, P.G., "A small molecule inducer of β cell proilferation indentified by high-throughput screening." J. Am. Chem. Soc., 135(5):1669-72, 2013..
511. Lairson, L. L., Lyssiotis, C.A., Zhu, S., Schultz, P.G., "Small molecule-based approaches to adult stem cell therapies." Ann. Rev. Pharmacol. Toxicol, 53:107-25, 2013.
510. Kazane, S.A., Axup, A.Y., Kim, C., Ciobanu, M., Wold, E.D., Barluenga, S., Hutchins, B.A., Schultz, P.G., Winssinger, N., Smider, V.V. "Self-assembled antibody multimers through peptide nucleic acid conjugation." J. Am. Chem. Soc., 135(1):340-6, 2013.
509. Axup, J.A., Bajjuri, K.M., Ritland, M., Hutchins, B.M., Kim, C., Kazane, S.A., Halder, R., Forsyth, J.S., Santidrian, A.F., Stafin, K., Liu, Y., Tran, H., Seller, A.J., Biroc, S.L., Szydlik, A., Pinkstaff, J.K., Tian, F., Sinha, S.C., Felding-Habermann, B., Smider, V.V., Schultz, P.G. "Synthesis of site-specific antibody-drug conjugates using unnatural amino acids." Proc. Nat. Acad. Sci., 109(40):16101-16106, 2012.
508. Guo, J., Wang, F., Schultz, P.G. "Unnatural amino acid mutagensis of fluorescent proteins." Angewante Chemie, 51(40):10132-10135, 2012.
507. Wang, D., Wang, J., Meeusen, S., Bonamy, G., Brusch, R.G., Turk, C., Yang, P., Schultz, P.G. "A small molecule promotes mitochondrial fusion in mammalian cells." Angewante Chemie Int. Ed. Engl, 51(40):10132-10135, 2012.
506. Hirota, T., Lee, J.W., St. John., P.C., Sawa, M., Iwaisako, K., Noguchi, T., Pongsawakul, P.Y., Sonntag, T., Welsh, D.K., Brenner, D.A., Doyle, J., Schultz, P.G., Kay, S.A. "Identification of small molecule activators of cryptochrome." Science, 337(6098):1094-1097, 2012.
505. Boitano, A.E., de Lichtervelde, L., Snead, J.L., Cooke, M.P., Schultz, P.G. "A platelet derived growth factor receptor antagonist." Proc. Nat. Acad. Sci, 109(35):14019-14022, 2012.
504. Chatterjee, A., Xiao, H., Schultz, P.G. "Evolution of multiple, mutally orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli." Proc. Nat. Acad. Sci., 109(37):14841-14846, 2012.
503. de Lichtervelde, L., Antal, C.E., Boitano, A.E., Wang, Y., Krastel, P., Petersen, F., Newton, A.C., Cooke, M.P., Schultz, P.G. "Euphohelisocopin A is a PKC activator capable of inducing macrophage differentiation." Chemistry and Biology, 19(8):944-1000, 2012.
502. Kim, C., Kang, M., Kim, H., Chatterjee, A., Schultz, P.G. "Site-specific incorporation of ε-N-crotonyllysine into histones." Angew. Chem., 51(29):7246-9, 2012.
501. Dubrovska, A., Hartung, A., Bouchez, L.C., Walker, J.R., Cho, C.Y., Schultz, P.G. "CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signaling." Br. J. Cancer, 107(1):43-52, 2012.
500. Kim, C., Axup, J.Y., Dubrovska, A., Kazane, S.A., Hutchins, B.A., Wold, E., Smider, V.V., Schultz, P.G. "Synthesis of bispecific antibodies with genetically encoded unnatural amino acids." J. Am. Chem. Soc., 134(24):9918-21, 2012.